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anti acvr1 alk2 rabbit polyclonal antibody  (Novus Biologicals)


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    Novus Biologicals anti acvr1 alk2 rabbit polyclonal antibody
    Figure1. GeneratingdoublemutantmicedeficientinBmpr1aandBmpr1b.A–C,CoronalsectionsthroughthetelencephalonofcontrolmiceatE11.5,processedwithinsituhybridizationtoshow expression of Bmpr1a (A), Bmpr1b (B), and a third type I BMP receptor gene, <t>Alk2</t> (C). Bmpr1a is expressed throughout the telencephalic neuroepithelium including the cortical hem; Bmpr1b is expressedmoreselectivelyinthedorsaltelencephalonwithahotspotofexpressionatthehem;Alk2isexpressedbroadlyinthedorsalandventraltelencephalon,butnotinthecorticalhem(C,C). D,BreedingstrategyusedtogeneratemicelackingBmpr1bconstitutivelyandBmpr1aconditionally,theBmpr1afx /;Bmpr1b /;Emx1 /IREScredoublemutantgenotype.E,PCRanalysisofDNA extracted from the tail and telencephalon of E12.5 Bmpr1afx /;Emx1 /IREScre and Bmpr1afx / mice. Primers fx1 and fx4 (Mishina et al., 2002) amplified a 180 bp fragment from Bmpr1afx /; Emx1 /IREScretelencephalon(lane4),indicativeofCre-mediatedrecombinationofBmpr1afx.The180bp“recombined”bandwasnotamplifiedfromtailtissue(lane2)orBmpr1afx /telencephalon (lane 6). Primers fx3 and fx5 amplified a 190 bp fragment from the Bmpr1a constitutive null allele in all three tissue samples (lanes 1, 3, 5). F, G, Coronal sections through the hem region at E12.5 inacontrolmouse(c)andadoublemutant(dm),immunostainedforpSmad1/5/8,transcriptionfactorsactivateddownstreamofBMPsignaling.TheredarrowsindicatepSmad1/5/8-IRcellsinthe controlhem(F)butvirtuallynopSmad1/5/8-IRcellsinthedoublemutanthem(G).Outsidethehem,inthehippocampalprimordium,pSmad1/5/8-IRcellsaredensealongtheventricularsurface (F,G).H,I,Ayoungadultcontrolmouse(H)andlittermatedoublemutant(I).Thedoublemutantisslightlysmallerthanthecontrol;theredarrowsindicatetruncateddigitsandpartiallossoffacial hair(seeResults).Abbreviations:hem,Corticalhem;hp,hippocampus;lge,lateralganglioniceminence;mge,medialganglioniceminence;ncx,neocortex;th,thalamus.Scalebar:(inA)A–C,200 m; C, 100 m; F, G, 50 m.
    Anti Acvr1 Alk2 Rabbit Polyclonal Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+acvr1+alk2+rabbit+polyclonal+antibody/Activin+RIA%2FALK-2%2FActivin+Receptor+Type+1+Antibody/10__1523_slash_jneurosci__0550___10__2010-60-114-120
    Average 86 stars, based on 1 article reviews
    anti acvr1 alk2 rabbit polyclonal antibody - by Bioz Stars, 2026-10
    86/100 stars

    Images

    1) Product Images from "Bone Morphogenetic Protein Signaling in the Developing Telencephalon Controls Formation of the Hippocampal Dentate Gyrus and Modifies Fear-Related Behavior"

    Article Title: Bone Morphogenetic Protein Signaling in the Developing Telencephalon Controls Formation of the Hippocampal Dentate Gyrus and Modifies Fear-Related Behavior

    Journal: Journal of Neuroscience

    doi: 10.1523/jneurosci.0550-10.2010

    Figure1. GeneratingdoublemutantmicedeficientinBmpr1aandBmpr1b.A–C,CoronalsectionsthroughthetelencephalonofcontrolmiceatE11.5,processedwithinsituhybridizationtoshow expression of Bmpr1a (A), Bmpr1b (B), and a third type I BMP receptor gene, Alk2 (C). Bmpr1a is expressed throughout the telencephalic neuroepithelium including the cortical hem; Bmpr1b is expressedmoreselectivelyinthedorsaltelencephalonwithahotspotofexpressionatthehem;Alk2isexpressedbroadlyinthedorsalandventraltelencephalon,butnotinthecorticalhem(C,C). D,BreedingstrategyusedtogeneratemicelackingBmpr1bconstitutivelyandBmpr1aconditionally,theBmpr1afx /;Bmpr1b /;Emx1 /IREScredoublemutantgenotype.E,PCRanalysisofDNA extracted from the tail and telencephalon of E12.5 Bmpr1afx /;Emx1 /IREScre and Bmpr1afx / mice. Primers fx1 and fx4 (Mishina et al., 2002) amplified a 180 bp fragment from Bmpr1afx /; Emx1 /IREScretelencephalon(lane4),indicativeofCre-mediatedrecombinationofBmpr1afx.The180bp“recombined”bandwasnotamplifiedfromtailtissue(lane2)orBmpr1afx /telencephalon (lane 6). Primers fx3 and fx5 amplified a 190 bp fragment from the Bmpr1a constitutive null allele in all three tissue samples (lanes 1, 3, 5). F, G, Coronal sections through the hem region at E12.5 inacontrolmouse(c)andadoublemutant(dm),immunostainedforpSmad1/5/8,transcriptionfactorsactivateddownstreamofBMPsignaling.TheredarrowsindicatepSmad1/5/8-IRcellsinthe controlhem(F)butvirtuallynopSmad1/5/8-IRcellsinthedoublemutanthem(G).Outsidethehem,inthehippocampalprimordium,pSmad1/5/8-IRcellsaredensealongtheventricularsurface (F,G).H,I,Ayoungadultcontrolmouse(H)andlittermatedoublemutant(I).Thedoublemutantisslightlysmallerthanthecontrol;theredarrowsindicatetruncateddigitsandpartiallossoffacial hair(seeResults).Abbreviations:hem,Corticalhem;hp,hippocampus;lge,lateralganglioniceminence;mge,medialganglioniceminence;ncx,neocortex;th,thalamus.Scalebar:(inA)A–C,200 m; C, 100 m; F, G, 50 m.
    Figure Legend Snippet: Figure1. GeneratingdoublemutantmicedeficientinBmpr1aandBmpr1b.A–C,CoronalsectionsthroughthetelencephalonofcontrolmiceatE11.5,processedwithinsituhybridizationtoshow expression of Bmpr1a (A), Bmpr1b (B), and a third type I BMP receptor gene, Alk2 (C). Bmpr1a is expressed throughout the telencephalic neuroepithelium including the cortical hem; Bmpr1b is expressedmoreselectivelyinthedorsaltelencephalonwithahotspotofexpressionatthehem;Alk2isexpressedbroadlyinthedorsalandventraltelencephalon,butnotinthecorticalhem(C,C). D,BreedingstrategyusedtogeneratemicelackingBmpr1bconstitutivelyandBmpr1aconditionally,theBmpr1afx /;Bmpr1b /;Emx1 /IREScredoublemutantgenotype.E,PCRanalysisofDNA extracted from the tail and telencephalon of E12.5 Bmpr1afx /;Emx1 /IREScre and Bmpr1afx / mice. Primers fx1 and fx4 (Mishina et al., 2002) amplified a 180 bp fragment from Bmpr1afx /; Emx1 /IREScretelencephalon(lane4),indicativeofCre-mediatedrecombinationofBmpr1afx.The180bp“recombined”bandwasnotamplifiedfromtailtissue(lane2)orBmpr1afx /telencephalon (lane 6). Primers fx3 and fx5 amplified a 190 bp fragment from the Bmpr1a constitutive null allele in all three tissue samples (lanes 1, 3, 5). F, G, Coronal sections through the hem region at E12.5 inacontrolmouse(c)andadoublemutant(dm),immunostainedforpSmad1/5/8,transcriptionfactorsactivateddownstreamofBMPsignaling.TheredarrowsindicatepSmad1/5/8-IRcellsinthe controlhem(F)butvirtuallynopSmad1/5/8-IRcellsinthedoublemutanthem(G).Outsidethehem,inthehippocampalprimordium,pSmad1/5/8-IRcellsaredensealongtheventricularsurface (F,G).H,I,Ayoungadultcontrolmouse(H)andlittermatedoublemutant(I).Thedoublemutantisslightlysmallerthanthecontrol;theredarrowsindicatetruncateddigitsandpartiallossoffacial hair(seeResults).Abbreviations:hem,Corticalhem;hp,hippocampus;lge,lateralganglioniceminence;mge,medialganglioniceminence;ncx,neocortex;th,thalamus.Scalebar:(inA)A–C,200 m; C, 100 m; F, G, 50 m.

    Techniques Used: Expressing, Amplification

    Related Articles

    Immunohistochemistry:

    Article Title: Bone Morphogenetic Protein Signaling in the Developing Telencephalon Controls Formation of the Hippocampal Dentate Gyrus and Modifies Fear-Related Behavior
    Article Snippet: .. For immunohistochemistry, primary antibodies were as follows: antiphospho-Smad1 (Ser463/465)/Smad5 (Ser463/465)/Smad8 (Ser426/ 428) rabbit polyclonal antibody (1:50; Cell Signaling Technology), antiphosphohistone H3 (PH3) (Ser10) rabbit polyclonal antibody (1:200; Millipore), anti-calbindin D-28K rabbit polyclonal antibody (1:250; Millipore Bioscience Research Reagents), anti-neuronal nuclei (NeuN) mouse monoclonal antibody (1:10; Millipore), anti-5-bromo-2-deoxyuridine (BrdU) mouse monoclonal antibody (1:75; BD Biosciences) for IHC and anti-BrdU mouse monoclonal antibody (1:50; Serotec) for immunofluorescence, anti-tyrosine hydroxylase (TH) antibody (1:5000; BD Biosciences), anti- -tubulin (Tuj1) (1:500; Covance), anti-Axin2 rabbit polyclonal antibody (1:5000; Abcam), anti-Olig2 rabbit polyclonal antibody (1:1000; Abcam), anti-(cleaved) caspase 3 rabbit polyclonal antibody (1:200; Cell Signaling), anti-Dickkopf1 (DKK1) rabbit polyclonal antibody (1:2000; Santa Cruz Biotechnology), anti-calretinin rabbit polyclonal antibody (1:1000; Millipore), and anti-Acvr1 (ALK2) rabbit polyclonal antibody (1:2000; Novus Biologicals). ..

    Immunofluorescence:

    Article Title: Bone Morphogenetic Protein Signaling in the Developing Telencephalon Controls Formation of the Hippocampal Dentate Gyrus and Modifies Fear-Related Behavior
    Article Snippet: .. For immunohistochemistry, primary antibodies were as follows: antiphospho-Smad1 (Ser463/465)/Smad5 (Ser463/465)/Smad8 (Ser426/ 428) rabbit polyclonal antibody (1:50; Cell Signaling Technology), antiphosphohistone H3 (PH3) (Ser10) rabbit polyclonal antibody (1:200; Millipore), anti-calbindin D-28K rabbit polyclonal antibody (1:250; Millipore Bioscience Research Reagents), anti-neuronal nuclei (NeuN) mouse monoclonal antibody (1:10; Millipore), anti-5-bromo-2-deoxyuridine (BrdU) mouse monoclonal antibody (1:75; BD Biosciences) for IHC and anti-BrdU mouse monoclonal antibody (1:50; Serotec) for immunofluorescence, anti-tyrosine hydroxylase (TH) antibody (1:5000; BD Biosciences), anti- -tubulin (Tuj1) (1:500; Covance), anti-Axin2 rabbit polyclonal antibody (1:5000; Abcam), anti-Olig2 rabbit polyclonal antibody (1:1000; Abcam), anti-(cleaved) caspase 3 rabbit polyclonal antibody (1:200; Cell Signaling), anti-Dickkopf1 (DKK1) rabbit polyclonal antibody (1:2000; Santa Cruz Biotechnology), anti-calretinin rabbit polyclonal antibody (1:1000; Millipore), and anti-Acvr1 (ALK2) rabbit polyclonal antibody (1:2000; Novus Biologicals). ..



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    anti acvr1 alk2 rabbit polyclonal antibody  (Novus Biologicals)
    86
    Novus Biologicals anti acvr1 alk2 rabbit polyclonal antibody
    Figure1. GeneratingdoublemutantmicedeficientinBmpr1aandBmpr1b.A–C,CoronalsectionsthroughthetelencephalonofcontrolmiceatE11.5,processedwithinsituhybridizationtoshow expression of Bmpr1a (A), Bmpr1b (B), and a third type I BMP receptor gene, <t>Alk2</t> (C). Bmpr1a is expressed throughout the telencephalic neuroepithelium including the cortical hem; Bmpr1b is expressedmoreselectivelyinthedorsaltelencephalonwithahotspotofexpressionatthehem;Alk2isexpressedbroadlyinthedorsalandventraltelencephalon,butnotinthecorticalhem(C,C). D,BreedingstrategyusedtogeneratemicelackingBmpr1bconstitutivelyandBmpr1aconditionally,theBmpr1afx /;Bmpr1b /;Emx1 /IREScredoublemutantgenotype.E,PCRanalysisofDNA extracted from the tail and telencephalon of E12.5 Bmpr1afx /;Emx1 /IREScre and Bmpr1afx / mice. Primers fx1 and fx4 (Mishina et al., 2002) amplified a 180 bp fragment from Bmpr1afx /; Emx1 /IREScretelencephalon(lane4),indicativeofCre-mediatedrecombinationofBmpr1afx.The180bp“recombined”bandwasnotamplifiedfromtailtissue(lane2)orBmpr1afx /telencephalon (lane 6). Primers fx3 and fx5 amplified a 190 bp fragment from the Bmpr1a constitutive null allele in all three tissue samples (lanes 1, 3, 5). F, G, Coronal sections through the hem region at E12.5 inacontrolmouse(c)andadoublemutant(dm),immunostainedforpSmad1/5/8,transcriptionfactorsactivateddownstreamofBMPsignaling.TheredarrowsindicatepSmad1/5/8-IRcellsinthe controlhem(F)butvirtuallynopSmad1/5/8-IRcellsinthedoublemutanthem(G).Outsidethehem,inthehippocampalprimordium,pSmad1/5/8-IRcellsaredensealongtheventricularsurface (F,G).H,I,Ayoungadultcontrolmouse(H)andlittermatedoublemutant(I).Thedoublemutantisslightlysmallerthanthecontrol;theredarrowsindicatetruncateddigitsandpartiallossoffacial hair(seeResults).Abbreviations:hem,Corticalhem;hp,hippocampus;lge,lateralganglioniceminence;mge,medialganglioniceminence;ncx,neocortex;th,thalamus.Scalebar:(inA)A–C,200 m; C, 100 m; F, G, 50 m.
    Anti Acvr1 Alk2 Rabbit Polyclonal Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+acvr1+alk2+rabbit+polyclonal+antibody/Activin+RIA%2FALK-2%2FActivin+Receptor+Type+1+Antibody/10__1523_slash_jneurosci__0550___10__2010-60-114-120
    Average 86 stars, based on 1 article reviews
    anti acvr1 alk2 rabbit polyclonal antibody - by Bioz Stars, 2026-10
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Figure1. GeneratingdoublemutantmicedeficientinBmpr1aandBmpr1b.A–C,CoronalsectionsthroughthetelencephalonofcontrolmiceatE11.5,processedwithinsituhybridizationtoshow expression of Bmpr1a (A), Bmpr1b (B), and a third type I BMP receptor gene, Alk2 (C). Bmpr1a is expressed throughout the telencephalic neuroepithelium including the cortical hem; Bmpr1b is expressedmoreselectivelyinthedorsaltelencephalonwithahotspotofexpressionatthehem;Alk2isexpressedbroadlyinthedorsalandventraltelencephalon,butnotinthecorticalhem(C,C). D,BreedingstrategyusedtogeneratemicelackingBmpr1bconstitutivelyandBmpr1aconditionally,theBmpr1afx /;Bmpr1b /;Emx1 /IREScredoublemutantgenotype.E,PCRanalysisofDNA extracted from the tail and telencephalon of E12.5 Bmpr1afx /;Emx1 /IREScre and Bmpr1afx / mice. Primers fx1 and fx4 (Mishina et al., 2002) amplified a 180 bp fragment from Bmpr1afx /; Emx1 /IREScretelencephalon(lane4),indicativeofCre-mediatedrecombinationofBmpr1afx.The180bp“recombined”bandwasnotamplifiedfromtailtissue(lane2)orBmpr1afx /telencephalon (lane 6). Primers fx3 and fx5 amplified a 190 bp fragment from the Bmpr1a constitutive null allele in all three tissue samples (lanes 1, 3, 5). F, G, Coronal sections through the hem region at E12.5 inacontrolmouse(c)andadoublemutant(dm),immunostainedforpSmad1/5/8,transcriptionfactorsactivateddownstreamofBMPsignaling.TheredarrowsindicatepSmad1/5/8-IRcellsinthe controlhem(F)butvirtuallynopSmad1/5/8-IRcellsinthedoublemutanthem(G).Outsidethehem,inthehippocampalprimordium,pSmad1/5/8-IRcellsaredensealongtheventricularsurface (F,G).H,I,Ayoungadultcontrolmouse(H)andlittermatedoublemutant(I).Thedoublemutantisslightlysmallerthanthecontrol;theredarrowsindicatetruncateddigitsandpartiallossoffacial hair(seeResults).Abbreviations:hem,Corticalhem;hp,hippocampus;lge,lateralganglioniceminence;mge,medialganglioniceminence;ncx,neocortex;th,thalamus.Scalebar:(inA)A–C,200 m; C, 100 m; F, G, 50 m.

    Journal: Journal of Neuroscience

    Article Title: Bone Morphogenetic Protein Signaling in the Developing Telencephalon Controls Formation of the Hippocampal Dentate Gyrus and Modifies Fear-Related Behavior

    doi: 10.1523/jneurosci.0550-10.2010

    Figure Lengend Snippet: Figure1. GeneratingdoublemutantmicedeficientinBmpr1aandBmpr1b.A–C,CoronalsectionsthroughthetelencephalonofcontrolmiceatE11.5,processedwithinsituhybridizationtoshow expression of Bmpr1a (A), Bmpr1b (B), and a third type I BMP receptor gene, Alk2 (C). Bmpr1a is expressed throughout the telencephalic neuroepithelium including the cortical hem; Bmpr1b is expressedmoreselectivelyinthedorsaltelencephalonwithahotspotofexpressionatthehem;Alk2isexpressedbroadlyinthedorsalandventraltelencephalon,butnotinthecorticalhem(C,C). D,BreedingstrategyusedtogeneratemicelackingBmpr1bconstitutivelyandBmpr1aconditionally,theBmpr1afx /;Bmpr1b /;Emx1 /IREScredoublemutantgenotype.E,PCRanalysisofDNA extracted from the tail and telencephalon of E12.5 Bmpr1afx /;Emx1 /IREScre and Bmpr1afx / mice. Primers fx1 and fx4 (Mishina et al., 2002) amplified a 180 bp fragment from Bmpr1afx /; Emx1 /IREScretelencephalon(lane4),indicativeofCre-mediatedrecombinationofBmpr1afx.The180bp“recombined”bandwasnotamplifiedfromtailtissue(lane2)orBmpr1afx /telencephalon (lane 6). Primers fx3 and fx5 amplified a 190 bp fragment from the Bmpr1a constitutive null allele in all three tissue samples (lanes 1, 3, 5). F, G, Coronal sections through the hem region at E12.5 inacontrolmouse(c)andadoublemutant(dm),immunostainedforpSmad1/5/8,transcriptionfactorsactivateddownstreamofBMPsignaling.TheredarrowsindicatepSmad1/5/8-IRcellsinthe controlhem(F)butvirtuallynopSmad1/5/8-IRcellsinthedoublemutanthem(G).Outsidethehem,inthehippocampalprimordium,pSmad1/5/8-IRcellsaredensealongtheventricularsurface (F,G).H,I,Ayoungadultcontrolmouse(H)andlittermatedoublemutant(I).Thedoublemutantisslightlysmallerthanthecontrol;theredarrowsindicatetruncateddigitsandpartiallossoffacial hair(seeResults).Abbreviations:hem,Corticalhem;hp,hippocampus;lge,lateralganglioniceminence;mge,medialganglioniceminence;ncx,neocortex;th,thalamus.Scalebar:(inA)A–C,200 m; C, 100 m; F, G, 50 m.

    Article Snippet: For immunohistochemistry, primary antibodies were as follows: antiphospho-Smad1 (Ser463/465)/Smad5 (Ser463/465)/Smad8 (Ser426/ 428) rabbit polyclonal antibody (1:50; Cell Signaling Technology), antiphosphohistone H3 (PH3) (Ser10) rabbit polyclonal antibody (1:200; Millipore), anti-calbindin D-28K rabbit polyclonal antibody (1:250; Millipore Bioscience Research Reagents), anti-neuronal nuclei (NeuN) mouse monoclonal antibody (1:10; Millipore), anti-5-bromo-2-deoxyuridine (BrdU) mouse monoclonal antibody (1:75; BD Biosciences) for IHC and anti-BrdU mouse monoclonal antibody (1:50; Serotec) for immunofluorescence, anti-tyrosine hydroxylase (TH) antibody (1:5000; BD Biosciences), anti- -tubulin (Tuj1) (1:500; Covance), anti-Axin2 rabbit polyclonal antibody (1:5000; Abcam), anti-Olig2 rabbit polyclonal antibody (1:1000; Abcam), anti-(cleaved) caspase 3 rabbit polyclonal antibody (1:200; Cell Signaling), anti-Dickkopf1 (DKK1) rabbit polyclonal antibody (1:2000; Santa Cruz Biotechnology), anti-calretinin rabbit polyclonal antibody (1:1000; Millipore), and anti-Acvr1 (ALK2) rabbit polyclonal antibody (1:2000; Novus Biologicals).

    Techniques: Expressing, Amplification